Hydroporation With Jetpeel Dermalinfusion
- An Analysis Of Efficacy


Beautyful skin causes in physical attractiviness. Therefore cosmetic procedures should optimize parameters like skin glow and elasticity.

Jetpeel is a device for cosmetic resurfacing of the facial skin. It is based on a technology of a 2-phase stream that creates a jet composed of high pressure air flux delivery, including oxygen, mixed with different chemical compounds sucand microdroplets of saline or for example antioxidants, vitamins and hyaluronic acid accelerated to supersonic velocities. This jet impacts the skin, causing gentle and accurate cosmetic peeling.

In this half side, randomized controlled split face trail we evaluated the effects of a new hydroporation method.

Methods & material

In this randomized, double-blind, half-side comparison of 6 weeks duration 20 healthy females (aged 20 – 45 years) with signs of skin aging were randomized to receive a treatment with a hyaluronic acid solution applied with the Jetpeel (figure 2) at one side of the face and a saline peeling at the contralateral side.

Efficacy was assessed at baseline and after treatment using a subject questionnaire. Additionally biophysical assessments of surface topography (Primos®, GFMesstechnik GmbH, Berlin, Germany), skin elasticity (Cutometer® MPA 580) and skin hydration (Corneometer® CM 825) were also performed. To evaluate the tolerance of the treatment pH-value (Skin-pH-Meter® PH905), transepidermal waterloss (Tewameter® TM 300, all Courage & Khazaka, Cologne, Germany) were performed and furthermore subjects were asked to keep a project diary. Pictures were performed by using Visia System (Canfield, Fairfield, USA)

Study Design



Fig. 2: Treatment with Jetpeel


After 6 treatments using saline solution and delivering by hyaluronic acid with Jetpeel skin quality improved in all subjects. There was a clinical improvement of wrinkle severity according to the evaluation of skin topography. Skin netto elasticity increased by 14,8%, brutto elasticity by 4,8%. Skin surface hydration evaluated by corneometry improved from 63,64 to 65,05.

Results of the subject questionnaire showed a significant time effect for skin sensation (p = 0,005), skin glow (p ≤ 0,001), skin smoothness (p = 0,02) and skin hydration (p = 0,001). 95% of subjects were delight with the treatment. There were no reported side effects, moreover pH value and trans-epidermal waterloss remained in physiological range over the entire study period.

Fig. 3: standardized fotography at a) baseline and b) after a six week treatment with Jetpeel

Fig. 4: standardized photography at a) baseline and b) after a six week treatment wih Jetpeela

Fig. 5: Results of facial appearance self-perception questionnaire (* p<0.05, **p<0.01, ***p<0.001)[/fusion_text][/fusion_builder_column][fusion_builder_column row_column_index="3_7" type="1_2" last="yes" spacing="yes" center_content="no" hide_on_mobile="no" background_color="" background_image="" background_repeat="no-repeat" background_position="left top" border_size="0px" border_color="" border_style="" padding="" margin_top="" margin_bottom="" animation_type="" animation_direction="" animation_speed="0.1" class="" id=""][fusion_imageframe lightbox="no" lightbox_image="" style_type="none" bordercolor="" bordersize="0px" borderradius="0" stylecolor="" align="none" link="" linktarget="_self" animation_type="0" animation_direction="down" animation_speed="0.1" hide_on_mobile="no" class="" id=""] [/fusion_imageframe]Fig. 6: Results of skin elasticity (arbitrary values)

Fig. 7: Results of corneometry (arbitrary values)

Fig. 8: Results of skin topography a) at baseline, b) after six week of treatment


The evaluated cosmetic procedure proved to be an effective option for non-invasive application of hyaluronic acid. It improves skin glow, smoothness and hydration and is accombiened with a high subjects` satisfaction. Furthermore it s well tolerated.

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